According to Killzone 2 devs, the PS3 is easier to develop for than the 10 year old PS2. Herman Hulst, managing director of Guerrilla Games had this to say about developing for PS3.
“If you are native to PlayStation, our tech director doesn’t say it’s particularly difficult. It’s specific, but it’s not difficult like PS2 was difficult – PS2 was difficult to crack, but PS3 didn’t take us a long time to get up and running.”
Hulst concluded that multiplatform developers could have more issues because the PlayStation 3 “is very different” from other consoles. Though that’s not all, as another Guerrilla Games employee, developer director Arjan Brussee, added:
“I actually think PS3 is a simpler architecture than some of the other consoles; you just have to have a certain mindset on how to address it. I think the Cell-based processor with the SPUs and the super high speed DSPs that you can throw all your calculation tasks at gives us a model that’s way easier to program for, even for junior programmers, than the general purpose multi-core type of architecture, which the PC and Xbox 360 have.”
[Source]