Main Game Trophies:
- .. .- — .- .-.. .. …- . (Silver) Solve all of Subject 16’s Puzzles.
- A Knife to the Heart (Gold) Secure the Apple of Eden.
- Abstergo Employee of the Month (Bronze) Get every single bonus at least once (Multiplayer Only).
- Ahead of the Curve (Bronze) Perform a double or a triple escape (Multiplayer Only).
- Amen (Silver) Discover the Shrine in the Basillica di San Pietro.
- Bang! (Bronze) Destroy the Machine Gun.
- Battle Wounds (Silver) Complete DNA Sequence 1
- Bloody Sunday (Silver) Complete DNA Sequence 7.
- Boom! (Bronze) Destroy the Bomber.
- Brotherhood (Bronze) Recruit 3 Assassins.
- Capture the Flag (Bronze) Remove All Borgia Flags in Rome.
- Déjà vu (Bronze) Replay a Memory.
- Download Complete (Silver) Reach Level 50 (Multiplayer Only).
- Dust to Dust (Bronze) Find 1 Artifact in 2012.
- Fast Learner (Bronze) Kill your target and escape your pursuer in less than 10 seconds (Multiplayer Only).
- Fixer-Upper (Silver) Complete DNA Sequence 3.
- Fly Like an Eagle (Bronze) Jump with the parachute off the top of the Castel Sant’Angelo.
- Forget Paris (Silver) Complete DNA Sequence 6.
- Fundraiser (Silver) Complete DNA Sequence 5.
- Gladiator (Silver) Discover the Shrine in Il Colosseo.
- Golden Boy (Bronze) Discover the Shrine in the Terme di Traiano.
- Home Improvement (Bronze) Renovate 5 buildings in the Antico district.
- In Memoriam (Bronze) Collect All Feathers.
- Job Skills (Silver) During Open Conflict, kill your target and escape (Multiplayer Only).
- Julius Caeser (Platinum) Win Every Trophy.
- Kaboom! (Bronze) Destroy the Tank.
- Mailer Daemon (Bronze) Access your Email in 2012.
- Needle in a Haystack (Bronze) Kill your target while being hidden in a hay bale (Multiplayer Only).
- One-Man Wrecking Crew (Silver) Discover the Shrine in Palazzo Laterano.
- Overachiever (Bronze) Score 750 points or more on a single kill (Multiplayer Only).
- Perfect Recall (Bronze) Achieve 100% Synchronization in any Sequence other than Sequence 1.
- Perfectionist (Bronze) Earn 3 gold medals in the Animus Virtual Training Program.
- Plumber (Silver) Discover the Shrine in the Cloaca Maxima.
- Principessa in Another Castello (Silver) Complete DNA Sequence 4.
- Requiescat In Pace (Bronze) Complete DNA Sequence 9.
- Role Model (Bronze) Get all the Co-op bonuses in 1 session (Multiplayer Only).
- Rome in Ruins (Silver) Complete DNA Sequence 2.
- Sanctuary! Sanctuary! (Bronze) Find a secure place to hide and re-enter the Animus.
- Serial Killer (Bronze) Perform an Execution Streak of 10 kills.
- Show Off (Bronze) Complete 10 Guild Challenges.
- Splash! (Bronze) Destroy the Naval Cannon.
- Spring Cleaning (Bronze) Kill a guard with a broom.
- Strong Closer (Bronze) Take the lead 10 seconds before the end of the session and win the game (Multiplayer Only).
- Synchronization Established (Bronze) Complete an entire Session with at least one kill (Multiplayer Only).
- Technical Difficulties (Bronze) Attempt to access DNA Sequence 9 for the first time.
- The Gloves Come Off (Bronze) Win the highest bet at the Fights.
- Tower Offense (Bronze) Burn All Borgia Towers.
- Undertaker 2.0 (Bronze) Discover the Shrine in the Catacombe di Roma.
- Vittoria Agli Assassini (Silver) Complete DNA Sequence 8.
- Welcome to the Brotherhood (Bronze) Train a recruit up to the Rank of Assassin.
- Your Wish is Granted (Bronze) Throw money in a well.
