Main Game Trophies:
- 100 Headshots (Bronze) Defeat 100 enemies with headshots.
- 200 Kills: GAU – 19 (Bronze) Defeat 200 enemies with the GAU – 19.
- 250 Headshots (Silver) Defeat 250 enemies with headshots.
- 30 Kills: Desert – 5 (Bronze) Defeat 30 enemies with the Desert – 5.
- 30 Kills: Mk – NDI (Bronze) Defeat 30 enemies with the Mk – NDI.
- 30 Kills: Moss – 12 (Bronze) Defeat 30 enemies with the Moss – 12.
- 30 Kills: RPG – 7 (Bronze) Defeat 30 enemies with the RPG – 7.
- 30 Kills: Wes – 44 (Bronze) Defeat 30 enemies with the Wes – 44.
- 50 Kills: 92FS – 9mm (Bronze) Defeat 50 enemies with the 92FS – 9mm.
- 50 Kills: Dragon Sniper (Bronze) Defeat 50 enemies with the Dragon Sniper.
- 50 Kills: GP32 – BND (Bronze) Defeat 50 enemies with the GP32 – BND.
- 50 Kills: M79 (Bronze) Defeat 50 enemies with the M79.
- 50 Kills: Micro – 9mm (Bronze) Defeat 50 enemies with the Micro – 9mm.
- 70 Kills: FAL (Bronze) Defeat 70 enemies with the FAL.
- 70 Kills: M4 (Bronze) Defeat 70 enemies with the M4.
- 70 Kills: SAS – 12 (Bronze) Defeat 70 enemies with the SAS – 12.
- Bare-knuckle Slugger (Silver) Defeat 50 enemies with hand-to-hand combat.
- Bounty: Arcana (Bronze) Complete the bounty set.
- Bounty: Cádiz (Bronze) Complete the bounty set.
- Bounty: Gemstones (Bronze) Complete the bounty set.
- Bounty: Pieces of Silver (Bronze) Complete the bounty set.
- Charted! – Crushing (Gold) Finish the game in Crushing Mode.
- Charted! – Easy (Bronze) Finish the game in Easy Mode.
- Charted! – Hard (Gold) Finish the game in Hard Mode.
- Charted! – Normal (Silver) Finish the game in Normal Mode.
- Hangman (Bronze) Defeat 20 enemies with gunfire by aiming while hanging.
- Master Ninja (Silver) Defeat 50 enemies with stealth attacks.
- Odessa Mining Company (Bronze) Complete the Mystery.
- Paparazzo (Bronze) Complete all photographs.
- Platinum (Platinum) Collect all other 55 Trophies for this Trophy.
- Poisoned Powder (Bronze) Complete the Mystery.
- Proof of Life (Bronze) Complete the Mystery.
- Puzzle Master (Bronze) Complete all puzzles.
- Relic Finder (Bronze) Find the strange relic.
- Rub One Out (Bronze) Complete all rubbings.
- Ruffle My Feathers (Bronze) Force José Parrot to squawk out 8 unique quips.
- Run-and-Gunner (Bronze) Defeat 20 enemies by shooting from the hip (without aiming).
- Secrets of the Kuna (Bronze) Complete the Mystery.
- Steel Fist Expert (Silver) Defeat 10 enemies in a row with a single punch, after softening them up with gunfire.
- Steel Fist Master (Bronze) Defeat 20 enemies with a single punch, after softening them up with gunfire.
- Survivor (Bronze) Defeat 75 Enemies in a row without dying.
- The Circle of Heaven (Bronze) Complete the Mystery.
- The Collector (Bronze) Collect first treasure or mystery.
- The Conquistadors (Bronze) Complete the Mystery.
- The Friar’s Pilgrimage (Bronze) Complete the Mystery.
- The Lost Civilization (Bronze) Complete the Mystery.
- The Revolution (Bronze) Complete the Mystery.
- The Ring of Earth (Bronze) Complete the Mystery.
- The Sete Cidades (Bronze) Complete the Mystery.
- Touch My Rear (Bronze) Use the rear touch pad to climb a rope or chain.
- Trail of Vincent Perez (Bronze) Complete the Mystery.
- Treasure: Jade Carvings (Bronze) Complete the treasure set.
- Treasure: Minor Deities (Bronze) Complete the treasure set.
- Treasure: The Menagerie (Bronze) Complete the treasure set.
- Treasure: Turquoise Glyphs (Bronze) Complete the treasure set.
